This release is available in Spanish. Barcelona, Spain: Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today Wednesday 9 July. Con Mallidis from Queen's University, Belfast, UK, said that, despite the prevailing view that it had little effect on male reproductive function, the Belfast group had shown that diabetes caused DNA damage in sperm. The increase in the numbers of diabetics diagnosed at a young age has coincided with worldwide concerns over male fertility, he told the conference. The scientists studied semen samples from men with diabetes who were receiving insulin therapy. On initial routine microscopic examination the semen samples appeared normal, apart from a slight decrease in volume.
Sperm quality in adult diabetic men.
Men With Diabetes Have More Damaged Sperm DNA
The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis
In 65 adult diabetic men and 77 control men without diabetes, both groups without any problems as to fertility, the following characteristics of ejaculate have been compared: volume of seminal fluid, sperm concentration per milliliter, total sperm count, sperm morphology, and motility at 1, 3, and 5 hours after ejaculation. In the entire diabetic group, sperm morphology and motility at 1 hour after ejaculation was statistically significantly worse. In 15 diabetics without sexual disurbances only sperm morphology was statistically significantly worse compared with an equally large control groups.
New therapy? Researchers have used cells that develop into sperm to create a type of pancreatic cell blue that secrete insulin red , which may one day cure type 1 diabetes in men. Such transplants would eliminate the need for frequent daily insulin injections to control blood sugar.